Volunteers sought for PMS study | TahoeDailyTribune.com
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Volunteers sought for PMS study

Volunteers are being sought to participate in a research study for women who suffer from symptoms of severe PMS, also known as postmenstrual dysphoric disorder or PMDD. This placebo-controlled research study will evaluate the safety and effectiveness of an investigational medication for the treatment of symptoms related to PMDD.

Up to 75 percent of women experience some symptoms of PMS with their regular menstrual cycles; of this group 3 to 8 percent experience PMDD. While significant premenstrual mood and behavior changes in women have been noted since ancient times, formal diagnosis criteria were not proposed until 1987.

Premenstrual Duysphoric Disorder, or severe menstrual syndrome, is a biologically based medical condition characterized by severe mood swings and behavior changes. Anxiety, depression and irritability may be prominent, and physical symptoms that can induce tension, bloating and breast tenderness. Many of the psychological and physical symptoms of PMDD are highly linked to the bloating that occurs due to water retention. These symptoms occur one week prior to menstruation and cause impaired functioning in day-to-day activities and effect interpersonal relationships.



The investigational medication being treated in this clinical trial is unique in combining several hormonal activities to impact the physical symptoms and emotional instability that can have a debilitating effect on a woman’s quality of life.

Volunteers 18 through 40 years of age are currently being screened for participation in this important clinical trial being conducted nationwide. Qualified participants will receive study-related medication and study-related health assessments. Potential study volunteers should call 1-800-92-TRIAL for additional information.



The study is being supported in the Truckee Meadows region by West Valley Imaging and The ISIS Foundation.


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